Dear Colleague:

I am pleased to announce that Cambridge Healthtech Institute’s Third Annual forum on Fragment-Based Drug Discovery is being held April 28th – 29th, 2008 in La Jolla, CA as part of Drug Discovery Chemistry 2008. 

The fragment-based approach to drug design has potential for efficient progression into clinically successful compounds. Library design and computational ligand modeling to identify potential fragments, initial screening techniques, molecular optimization based on ligand/target characterization, linking, biological screens, and morphing-scaffold hopping will be explored to identify advances to meet the challenges in the process. Leading case studies will be highlighted.

Preliminary Topic List

•  Designing Improved Fragment Libraries

•  Screening Approaches: X-Ray Crystallography, NMR Screening 

•  Advances to Improve Screening Technology

•  Leading Strategies for Characterization and Optimization

•  Unique Approaches to Novel Target Sites 

• Clinical Case Studies

If you would like to submit a proposal to give a presentation or display a poster at this meeting please send us a brief summary of the proposed topic on your recent work. 

To ensure the quality of the program, all proposals will be reviewed by the scientific advisory committee.

The deadline for submission is November 9th.

Please click here to submit a proposal.

For questions or suggestions about the meeting, please contact: 
Tracy Webb, Ph.D.
Cambridge Healthtech Institute
250 First Avenue, Suite 300
Needham, MA 02494
Telephone: 781-972-5455
Email: twebb@healthtech.com