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CONFERENCE
ANNOUNCEMENT AND CALL FOR SPEAKER PROPOSALS
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 Cambridge
Healthtech Institute’s Third Annual...
G-Protein
Coupled Receptor Drug Discovery
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April 29-30,
2008 •
San Diego Marriott
• La Jolla, CA |
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About 50% of existing drugs work by targeting G-protein coupled receptors
(GPCRs), which remain an actively investigated class of drug targets. GPCRs represent the largest protein family in the human genome, and it is believed that about half of all GPCRs are pharmaceutically relevant. GPCRs are involved in many therapeutic areas including cardiovascular disease, inflammatory disease, CNS disorders, and metabolic disease. However, the functions of many GPCRs remain unknown, as do the natural ligands of many of these receptors. The lack of structural information makes it difficult to identify novel hits for
GPCRs.
CHI’s third annual G-Protein Coupled Receptor Drug Discovery conference will examine GPCR targets being pursued for new drug development, approaches for overcoming the challenges posed by this difficult target class, and tools to increase our knowledge of the structure, function and regulation of
GPCRs.
Conference coverage may include:
- GPCR-targeted libraries
- Functional and binding assays
- Fragment-based screening
- Peptidomimetic approaches
- Receptor dimerization
- Dual-target GPCR agonists/antagonists
- Allosteric modulation
- Inverse agonists
- De-orphanization
- GPCRs in clinical development
Interested in presenting? Researchers studying and/or targeting GPCRs for drug development are encouraged to submit a title and brief summary of their work for consideration.
To submit a proposal, please click here.
The deadline for submission (for priority consideration) is November
2, 2007.
For questions or suggestions about the meeting, please contact Laurie Sullivan at:
Cambridge Healthtech Institute
250 First Avenue, Suite 300
Needham, MA 02494
Telephone: (+1) 617-512-5295
Email: lsullivan17@comcast.net
For sponsorship information, please contact:
Suzanne Carroll
Cambridge Healthtech Institute
250 First Avenue, Suite 300
Needham, MA 02494
Telephone: 781-972-5452
Email: scarroll@healthtech.com
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