Hepatitis C Virus Polymerase Inhibitors in Development

Structure-Based Design of Non-Nucleoside NS5B Inhibitors for the Treatment of HCV
R. Than Hendricks, Ph.D., Principal Research Scientist, Medicinal Chemistry, Roche Palo Alto

Hepatitis C Virus Protease Inhibitors in Development

Discovery of the Macrocyclic HCV Protease Inhibitor TMC435350
Pierre Raboisson, Ph.D., HCV Disease Area Chemistry Leader, Tibotec BVBA

Discovery of MK-7009: A Novel Macrocyclic Inhibitor of HCV NS3/4A Protease 
Michael T. Rudd, Ph.D., Research Fellow, Medicinal Chemistry, Merck Research Laboratories

Other Mechanisms

A Peptide Inhibitor of the Hepatitis C Virus Core Protein Dimerization
A. Donny Strosberg, Ph.D., Professor, Department of Infectology, The Scripps Research Institute-Florida

Taribavirin: Discovery and Development of 2nd Generation of Ribavirin for Treatment of HCV Infection
Jim Z. Wu, Ph.D., Director, Preclinical and Translational Research, Global Drug Development, Valeant Pharmaceuticals International