TOOLS FOR TARGETING PROTEIN-PROTEIN INTERACTIONS

Protein-Protein Docking Simulations for Hot-Spot Identification and Drug Design
Juan Fernandez-Recio, Ph.D., Research Group Leader, Life Sciences, Barcelona Supercomputing Center

The Rapid Creation and Screening of Conformation-Restricted Synthetic Libraries against Protein-Protein Interaction Targets
Stephen Hale, Ph.D., Senior Director, Discovery, Ensemble Discovery

Transient Pockets on Protein Surfaces Involved in Protein-Protein Interaction
Volkhard Helms, Ph.D., Chair of Computational Biology, Center for Bioinformatics, University of Saarland

CASE STUDIES AND APPLICATIONS

Inducing Programmed Cell Death in Cancer: A New Therapeutic Approach
Kurt Deshayes, Ph.D., Senior Scientist, Department of Protein Engineering, Genentech, Inc.

Structure-based Investigation of Wnt Signaling Inhibitors
Jie Zheng, Ph.D., Associate Member, Department of Structural Biology, St. Jude Children’s Research Hospital