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CONFERENCE ANNOUNCEMENT AND CALL FOR SPEAKER PROPOSALS

Cambridge Healthtech Institute’s Second Annual...
Protein-Protein Interactions as Drug Targets

April 29-30, 2008  • San Diego Marriott • La Jolla, CA

Protein-protein interactions (PPI) play a key role in many biological processes, making them promising targets for drug discovery. Though inhibition of protein-protein interactions has been challenging due to binding-site characteristics at the protein-protein interface, there has been considerable success in recent years. CHI’s Second Annual Protein-Protein Interactions as Drug Targets conference will examine PPI inhibitors that are either in or advancing toward the clinic, as well as the technologies enabling our understanding of how to successfully exploit this drug class. Building on the momentum from this year’s inaugural program, this meeting will seek to further explore the identification of protein-protein interaction pairs, modulation of intracellular protein-protein interactions, computational approaches, peptidomimetics, fragment-based screening, and more.

Sessions:
  • Targets for Drug Discovery
  • Technologies for Tackling
  • Case Studies and Applications

Conference coverage may include:

  • Identifying protein-protein interaction pairs
  • Modulating intracellular protein-protein interactions 
  • Challenges posed by binding-site characteristics – distinguishing hotspots 
  • Computational approaches – predicting protein-protein interactions, assessing druggability, structure-based design 
  • Designing and synthesizing peptidomimetics 
  • Fragment-based screening approaches
  • Case studies: 
    • Successful PPI inhibition: Challenges, PPI targets, potential therapeutic applications
    • PPI inhibitors in the clinic

Interested in presenting? Researchers targeting protein-protein interactions are encouraged to submit a title and brief summary of their work for consideration.
To ensure the quality of the program, all proposals will be reviewed by the scientific advisory committee.

To submit a proposal, please click here

The deadline for submission (for priority consideration) is October 26, 2007.

For questions or suggestions about the meeting, please contact Laurie Sullivan at:
Cambridge Healthtech Institute
250 First Avenue, Suite 300
Needham, MA 02494
Telephone: (+1) 617-512-5295
Email: lsullivan17@comcast.net  

For sponsorship information, please contact:
Suzanne Carroll
Cambridge Healthtech Institute
250 First Avenue, Suite 300
Needham, MA 02494
Telephone: 781-972-5452
Email: scarroll@healthtech.com

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