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Ernst & Young: 2006 Reveals Biotech’s Shifting Paradigm
By Laurie Sullivan

Biotechnology was once dubbed “one of the biggest money-losing industries in the history of mankind” by Arthur Levinson, chief executive officer of Genentech, but right now the global biotech industry is seemingly undergoing a sea change.

In 2006, it heralded advances of historic proportion, according to Beyond Borders: Global Biotechnology Report 2007, Ernst & Young’s 21st anniversary report on the biotechnology industry. The biotechnology sector “is comfortably on track to become a $100 billion revenue industry before the end of the decade,” said Glen Giovannetti, Ernst & Young’s global biotechnology leader, in a press release.

And the signs point in that direction: In 2006, global public biotech company revenues surpassed the $70 billion mark – a threshold heretofore uncrossed.

US Biotech: A Hair Trigger Away From Profitability

Last year was truly monumental for US biotech firms in their pursuit of bona fide profitability. If not for the more than $4 billion in acquired in-process R&D charges related to the year’s record-breaking deal activity (see below), the US publicly-traded sector would have shown an aggregate net profit for the first time.

Amongst the highlights from 2006, capital raised increased by 38%, and US revenue increased 13% to $59 billion. On a worldwide basis, capital raised increased by 42%, to $27.9 billion.

Deals, Deal, Deals … 2006’s Hallmarks

Alliances struck during 2006, involving US companies, totaled an unprecedented $23 billion. For the overall global biotech industry, the average premium in M&A transactions with values over $500 million increased to 60% in 2006 – catapulting last year’s M&A values to the second-highest level in the industry’s history.

In an interesting trend reversal, biotech’s pharmaceutical buyers showed a preference for early-stage platforms and technologies last year.

But even better, the trend is not likely to wane: An Ernst & Young survey of over 400 biotechnology CEOs found that a whopping 99% of Americas CEOs, and 87% of European CEOs, plan to enter deals within the next two years. Moreover, more than half of CEOs plan to partner in order to bring new products to market.

European Biotech Is Gaining Traction

The European biotech sector is experiencing a ground swell of heightened productivity. But just a few years ago, in 2003, it recorded a 12% revenue decline.

Since then, it has made pivotal progress: In 2006, its revenue grew 13% – more than twice the 2005 growth rate – to $16.6 billion. Yet perhaps an even bigger story is the landmark level of financing enjoyed by European biotechs in 2006, which increased by 45% to reach $5.9 billion.

Indeed, venture capital financings set a record at $1.9 billion. Worldwide, venture capital reached a previously unachieved figure of $5.4 billion.

The Rub?

So is biotech’s upswing accompanied by a dear price?

“Maturity brings greater responsibilities, including greater regulatory challenges and heightened investor scrutiny,” said Giovannetti.

That is, arguably, true enough. But if 2006 is any indication, the world’s biotech industry is ripe for the challenge.

Copyright 2007, Cambridge Healthtech Institute. All Rights Reserved.

 

 

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